学术沙龙:Intelligent 3D Cryo-EM Image Analysis for Next Generation Biomedicine

文:教师发展中心 / 来源:人力资源部 / 2017-06-19 / 点击量:921

  为加强我校各学科之间的学术交流,搭建教师学术交流平台,促进教师学术水平提升和跨学科合作,教师发展中心开展跨学科学术沙龙活动。

  本次活动教师发展中心特别邀请来自美国华盛顿大学的司栋助理教授,与我校师生分享他在信息医疗领域的研究心得。具体安排如下,欢迎感兴趣的师生参加:

  一、主 题:Intelligent 3D Cryo-EM Image Analysis for Next Generation Biomedicine

  二、主讲人:司栋博士(美国华盛顿大学助理教授)

  三、时 间:2017年6月20日(周二)15:00

  、地 点:清水河校区宾诺咖啡

  五、主持人:国家“青年千人”计划入选者 徐增林教授

  六、承办单位:计算机科学与工程学院、统计机器智能与学习实验室(SMILE Lab)

  七、交流内容:

  Life ultimately depends on the interactions of large biological molecules, such as proteins. The nature of these interactions depends on the three dimensional (3D) shape and structure of these molecules. Electron cryo-microscopy (cryo-EM) as a cutting edge technology has carved a niche for itself in the study of large-scale protein complex. The accuracy of secondary structures and backbone structure detection from the volumetric protein density images is critical for ab initio modeling in cryo-EM. So far it is challenging to detect the SSEs and backbone structures automatically and accurately from the density images at medium-high resolutions. We have combined image processing, machine learning and geometric modeling techniques and developed SSETracer, SSELearner, StrandTwister, StrandRoller, BarrelMiner along with recent developed deep learning framework to allow for the automatic and accurate prediction of secondary structures and backbone structures from experimental derived 3D cryo-EM images of protein complexes.

  八、主讲人简介:

  Dong Si is currently an assistant professor at University of Washington Bothell. He received his M.S. and Ph.D. in Computer Science from Old Dominion University Virginia, and his B.S. in Electronic Information Science from Nanjing University China. Over the years, Dong’s research has included visual data analytics, feature detection and pattern recognition, machine learning and data mining, geometric modeling, and computational structural bioinformatics. He is currently the lead guest editor of Journal of Molecular Based Mathematical Biology and reviewer of multiple international journals including BMC Bioinformatics and Journal of Data Mining and Bioinformatic. His also serves in the organizing and program committee for many international conferences including ACM-BCB. 


                     人力资源部教师发展中心

                       2017年6月19日


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